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Introduction:

• Participating institutions in Middlesex County and Thunder Bay
• Ontario Cancer Treatment and Research Foundation

Overview of Contents:

• Important Outstanding Issues
• Data Sharing
• Concurrent Development of Cytobase
• Funding

Sections:

• Section A: Demonstration of Feasibility in Two Geographic Areas
• Section B: Source Data Investigation in Middlesex County
• Section C: General System Design
• Section D: Data Security and Privacy Protocol
• Section E: Reporting Principles and Report Samples
• Section F: Evaluation Protocol

• A Legal Framework for Health Information: Consultation Paper
• Response to “Consultation Paper: A Legal Framework for Health Information” by Thunder Bay Cervical Screening Pilot Project Steering Committee. Presented by Dr. Eric Holowaty. Includes information about Ethics in Research, Current Law/Rules relating to Confidentiality of Health Information, etc.

Various emails:

• The Ontario Cancer Treatment and Research Foundation
• Ontario Cervical Screening Information and Reporting System
• Ontario Breast Screening Program-Northwestern Region

Draft: Screening for Squamous Cell Carcinoma of the Cervix (1995)

• Facts, Risk Factors, Recommendations

Terms of Reference – Steering Group: Thunder Bay Ocsirs Pilot

• Purpose, Composition, Specific Terms of Reference

Ocsirs Pilot Project

• Purpose
• Methods used in Middlesex County
• Method proposed for Thunder Bay

Report to the Members of the Board of the Ontario Cancer Treatment and Research Foundation

• Background
• Present Status

Draft: A Population-based information and reporting system for Cervical Screening in Ontario: Demonstration of Feasibility in 2 Geographic Areas (1995)

• Introduction, Objectives
• Present State of Knowledge
• Project Design
• Evaluation of Crisis
• Time Frame
• Related work and future research

Journal Article: Cervical Screening, Compliance and Moral Obligation by Alexandra Howson (1999)

Emails from Thunder Bay Regional Cancer Centre in regards to the program for “prevention of cervical cancer” in Northwestern Ontario (1993)

Various Memorandum for Files

• Cervical Cytology Screening Project – Dr. Nora Ho (May 19, 1993)
• Conversation with Jessica Hill and Dr. Nora Ho of the Ministry of Health (April 27th, 1993)
• Cervical Cancer Screening – Feasibility Study (June 8th, 1993)
• Conversation with Jessica Hill – Ministry of Health (January 8th, 1993)
• Cervical Cancer Screening (June 17, 1993)

• Case-Control Study of the Effectiveness of Cervical Cytology Screening in Northwestern Ontario (1975-1985)
• Research Project: Contribution of Cervical Cytology to Diagnosis of Carcinoma of Cervix in Northwestern Ontario from 1966 to 1986
• Cancer Cytology: Thunder Bay Case Control Study Protocol (August 24th, 1987)
• Ontario Cancer Treatment and Research Foundation
• Cervical Cancer: Coding Instructions
• A case study of the effectiveness of Cervical Cytology Screening in N.W. Ontario (1975-1986)

Literature:

• Background to Cervical Cytology Reports by Dr. Jennifer Hopwood. Includes information about Cytology of the Smear (General Appearance), Smear Reports, etc.
• Screening for Cancer of the Cervix Uteri by Elsebeth Lynge. Danish Cancer Registry and World Journal of Surgery. Includes Information about what is screening and the use of pap smears in Denmark.
• Staging and Surgical Therapy for Uterine Malignancies by Philip J. DiSaia. Includes information about Cervical cancer, advantages and disadvantages of surgical therapy.
• Cancer of the Cervix: Death by Incompetence
• Screening for Cervical Cancer by Aileen A. Clarke
• The Treatment of Invasive Cervical Carcinoma by Mark S. Carey
• How Frequently need vaginal smears be taken after hysterectomy for cervical intraepithelial neoplasia by J. Gemmell, D. M. Holmes, and I.D. Duncan.
• Cytology Office Manual by Cancer Control Agency of British Columbia and G.H. Anderson, J.C. Le Riche, L. Benedet, and O. Bennett.
• Cervical Cytology by A.B. Miller, 1985. Includes information about History of the Pap Smear, Requirements for a Pap Smear Screening Program, Collecting, Processing, and Screening of the Smear.
• Support for Pap Test Article by Scott Gibbons
• Short Report on Human Papillomavirus Type 16 DNA in cervical smears as predictor of high-grade cervical cancer. By Jack Cuzick, George Terry, Linda Ho, Tony Hollingworth, and Malcolm Anderson
• Multiple Carcinoma Same Cervix and Screening Results by J. Kotalik

• Objective
• Presentation Outline
• Format
• Schedule
• Membership (TBRH Ethics Committees)
• Action Plan

Handbook created by Francis Roberts Agency. Fourteenth Revision.

• Various articles on clinical trials
• Brochure on Randomized Trails in Cancer: A critical review by sites
• Clinical trials in cancer chemotherapy (1977) by Stephen K. Carter
• Article on the Conduct of Therapeutic Trails in Cancer Medicine (1977) by Seth Rudnick and Robert L. Capizzi
• A book on Cancer Therapy: Prognostic Factors and Criteria of Response (1975) by Maurice J.Staquet

• Article on the Ethics of the Randomized Clinical Trial
• Paper on Nephroblastoma (1979)
• Emails regarding clinical trials from University of Toronto (1985)
• Paper on Critical Evaluation of Clinical Trials in Oncology (1984)
• Article on Informed Consent for Investigational Chemotherapy (1984)
• Various special articles on clinical trials (1983-1984)
• Article on clinical trials and the treatment of cancer
• World Health Organization (1981) Cancer Research Article
• Seminars in Clinical Trials (1981)

1) Section I – Compliance Plans
2) Section II – Sample Plan
3) Appendix A – Specific Issues
4) Appendix B – Readings and Resources
5) Index

Various emails from Jaroslav Kotalik:

• Survey of Practitioners’ Views on Adjuvant Treatment for Node Negative Breast Cancer and Methods of Eliciting Women’s Preferences
• Toronto-Bayview Regional Cancer Centre

Draft of Cytology Computer Committee:

• Objectives

Estimate for Conducting a Feasibility Study of Computerized Information Management System for Cervical Cancer Screening in Northwestern Ontario:

• Objectives 1-2
• Points to Consider, Alternatives
• Margaret Green Resume

• Education
• Previous Employment
• Consultations
• Research Funding
• Publications

Includes information on:

• Clinical Coverage
• Telephone Directory
• Schedules (meetings, rounds, multidisciplinary clinics)
• Disease Site Protocols (Breast, Esophagus, Gynecology, Head and Neck, etc.)

Diagrams on:

• Colposcopy
• Screening Pyramind
• Ontario Cancer Registry (Years of Diagnosis of Females)
• Investigation of Abnormal Pap

• Prepared by: The Division of Preventive Oncology and Information Systems Department of Cancer Care Ontario
• Includes information on the Introduction, Methods and Result

• The Cancer Letter: Movemento Resolve Patient Care Reimbursement Problems Gains Momentum: NCI Report Adds Fuel. Volume 15. NO. 11, March 17th 1989.
• 1985 Cancer Statistics (Major Causes of Death - Males, Females, Different Types of Cancer)
• The Economics of Cancer Prevention and Detection: Getting More for Less by David M. Eddy (1981)
• Survey of Physicians’ Attitudes and Practices in Early Cancer Detection. Vol. 35 No.4 (July/August 1985) by the Cancer Journal for Clinicians.
• Article: A Debate Over Early Cancer Detection by Nora Underwood. Maclean’s, (January 27th 1986).
• Obstacles to Progress in Oncology by Jocelyn Chamberlain. Early Detection Cancer Screening
• Prevention of Cancer in the Cervix (Draft). Feasibility Study of Computerized Information Management System for Cervical Cancer Screening in Northwestern Ontario. Prepared by: Jaroslav F. Kotalik and Eric J. Holowaty (September 4th, 1993).
• Paper on the Effectiveness of Cervical Cancer Screening in Northwestern Ontario

• Author: Kristjan Sigurdsson
• 1993 Printed, Wiley-Liss, Inc.
• The Cancer Detection Clinic of the Icelandic Cancer-Society

Created by Dr. E.J. Holowaty
Information includes:

• Data collection of cervical cytology
• Cerivcal cytology coding instructions
• Results

J.F. Kotaik

Committee recommends that the hospital develops a comprehensive smoking policy for present buildings. Admission of smokers to the hospital results in ethical dilemma.

• The Role of Breast Self-Examination in Early Breast Cancer Detection
• Various Authors, 1992, Vol.8 No.4

• Canadian Association of Psychosocial Oncology (1989)
• Projected Budget (Revised)
• Project Budged (1989-1990)